Indications:
Oxanobol is indicated by the doctor when the following diseases happen: synthesis disorders, cachexia of diverse genesis; trauma, extensive burns after irradiation and infectious diseases; muscular dystrophy, osteoporosis, negative nitrogen balance corticosteroid therapy, hypo and aplastic anemia .
Contra- indications:
Oxanobol is not indicated by the doctor if patients have the following disorders: hypersensitivity to the drug, prostate cancer, breast cancer in men, breast carcinoma in women with hypercalcemia, ischemic heart disease, severe atherosclerosis, nephrotic syndrome, acute and chronic liver disease, including alcoholic nephritis, pregnancy, lactation.
Administration:
In adults, the doses are individually adjusted. An optimal dose for adults is 2.5-20 mg a day, cut into 2-4 doses.
Children use a dose of ≤ 0.1 mg / kg / day.
The therapy length is usually 2-4 weeks. The treatment cycle must be repeated after 1-2 months.
Medical action:
Oxanobol is an anabolic steroid. Getting into the cell nucleus it stimulates the genetic apparatus of the cell, which causes an increased synthesis of DNA, RNA and structural proteins, stimulates respiration tissue chain enzymes and enhances respiration tissue, oxidative phosphorylation, ATP synthesis and intracellular macroergic aggregation. This medicine stimulates anabolic processes and inhibits the catabolic ones caused by glucocorticoids. Oxymetholone can cause increased muscle mass, reduced fat deposits, improves trophic tissues, promotes calcium deposition in bones.t exhibits moderate androgenic action.
Precautions:
In case you feel first signs of virilization (deepening of the voice, hirsutism, acne, clitoromegaly) stop taking this medicine in order to avoid unwanted side effects. A systematic monitoring of lipidemic and cholesterol level is needed. The pediatric use must be done by an experienced specialist to avoid premature epiphyseal bone calcification.
Side effects:
Oxanobol can cause different side effects in women and men. They present different symptoms in men and women, but can be the same in some cases.
Women - virilizing signs, inhibition of ovarian function, menstrual disorders.
Men: in prepubertal - virilization symptoms, acne, withholding or stopping the growth (calcification of epiphyseal growth zones of tubular bones); during postpubertal - gynecomastia, priapism, inhibition of spermatogenesis.
Both men and women - the progression of atherosclerosis, peripheral edema, impaired liver function, changes in blood count, long tubular bones pain.
Overdosage:
In case, an overdose with Oxanobol happened seek emergency help.